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Allplex™ H. pylori & ClariR Assay

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The Allplex™ H. pylori & ClariR Assay is a multiplex real-time PCR test that detects and identifies H. pylori and the most common point mutations responsible for clarithromycin resistance in the H. pylori 23S rRNA gene. Key Benefits Comprehensive analysis: simultaneous detection...

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Industries

Clinical laboratory diagnostics Infectious diseases In-vitro diagnostics

Methods

Real-time PCR

Type

Reagents

Turnkey supply, installation and training · Service across Ukraine

The Allplex™ H. pylori & ClariR Assay is a multiplex real-time PCR test that detects and identifies H. pylori and the most common point mutations responsible for clarithromycin resistance in the H. pylori 23S rRNA gene.

Key Benefits

  1. Comprehensive analysis: simultaneous detection and identification of H. pylori and the major mutations (A2142G, A2143G, A2142C) responsible for clarithromycin resistance
  2. Multiplexing: individual Ct values for multiple analytes in a single channel of the real-time PCR instrument (MuDT™ technology)
  3. Use of the UDG system (a mixture containing uracil-DNA glycosylase) to prevent autocontamination during the preparation of PCR mixtures
  4. The test system complies with the requirements of the European Regulation on in vitro diagnostics, demonstrating compliance with European standards for safety, public health, and environmental protection (CE IVD)
  5. Convenient workflow: automatic data interpretation using the Seegene Viewer software module

Targets

  • A2142C
  • A2142G
  • A2143G
  • Helicobacter pylori (H. pylori)
  • Internal Control (IC)
Sample result presentation The result indicates the detection of H. pylori and the A2143G mutation in the FAM and HEX channels with Ct values of 29.83 and 28.91, respectively.  *Note: For use with the CFX96™ real-time PCR system (Bio-Rad)

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